pentobarbital will minimize the level or result of buspirone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will enhance the level or outcome of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
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Check Intently (2)pentobarbital will lessen the level or outcome of oliceridine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. If coadministration that has a CYP3A4 inducer is important, contemplate rising oliceridine dose right up until stable drug results are achieved; observe for indications of opioid withdrawal.
pentobarbital will lessen the extent or impact of fosaprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Contraindicated (1)pentobarbital will minimize the extent or result of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is to blame for the formation and elimination of cariprazine's active metabolites.
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pentobarbital will lower the level or impact of pantoprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will minimize the extent or impact of more info isradipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
pentobarbital will lessen the extent or outcome of midazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Contraindicated (1)pentobarbital will lessen the extent or impact of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the level or effect of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lessen the extent or effect of irinotecan liposomal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Barbiturates can induce hepatic microsomal enzymes resulting in enhanced metabolism and lessened anticoagulant response of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); individuals stabilized on anticoagulant therapy could call for dosage changes if barbiturates are added to or withdrawn from their dosage regimen